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The long-term outcome phase (months 4-12) establishes final post-treatment baseline revealing maximum durable benefits maintained without ongoing GHK-Cu use
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A 30-week dose of GLP-1 results in a 3.3 percent loss of weight and a drop in blood glucose A1C of 0.32 percentage points, changes that closely match clinical trial results
These findings position GLP-1RAs as a potential fourth pillar of kidney-protective therapy in diabetes, alongside renin-angiotensin system inhibitors (RASi), SGLT2i, and finerenone, and suggest a shift toward rapid initiation of combination therapies for maximum kidney protection
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